Fundamentals of futures and options markets 9th edition pdf40 comments
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When all patients with the risk factor presence also have the outcome), the likelihood function may not converge or converges in an unstable factor-outcome association.
For all case studies, in the two-stage models we used MLE in the first stage and MLE, REML or MOM in the second stage. For the one-stage models we used adaptive Gauss-Hermite Quadrature with 1 (Laplacian approximation) and 5 quadrature points. Assuming the random effects are normally distributed with between-study standard deviation, then an approximate prediction interval for the factor-outcome association in an unspecified study can be obtained as.